News
中文Events
- Update Date：2024-01-18
- Units：Laboratory Animal Center
ICCVAM Communities of Practice Webinar 2024
ICCVAM Communities of Practice Webinar 2024
Implementing Computational Approaches for Regulatory Safety Assessments
Monday, January 29, 2024 – 10:00 a.m.-12 noon EST
Register to view the webinar
Registration will be open until the webinar ends.
ICCVAM promotes the development and validation of toxicity testing methods that protect human health and the environment while replacing, reducing, or refining animal use. ICCVAM also provides guidance to test method developers and facilitates collaborations that promote the development of new test methods. This webinar, organized on behalf of ICCVAM by NICEATM, will discuss implementing computational approaches for regulatory safety assessments.
Computational toxicology methods can be useful for generating bioactivity predictions for chemicals for which limited toxicity data are available. They can also help users understand and interpret large, diverse bioactivity data sets, or predict how a chemical might behave in the body. However, users with limited experience with such methods may find it difficult to use them or interpret their outputs, or even understand how the methods could be applied in a specific context.
This webinar will discuss how to establish confidence in computational approaches for regulatory applications. Ongoing activities and key insights will be described in three presentations by speakers from the U.S. government and the private sector focusing on applications of tools such as structure-based models to predict chemical bioactivity and pharmacokinetic models to support understanding of chemical metabolism and disposition.
Agenda
Introductions: Helena Hogberg and Nicole Kleinstreuer, NIEHS/NICEATM
Presentations:
Michael Lowit, U.S. Environmental Protection Agency Office of Pesticide Programs
Pras Pathmanathan, U.S. Food and Drug Administration Center for Devices and Radiological Health
Jon Arnot, Arnot Research and Consulting
Q&A: Emily Reinke, Inotiv (contractor supporting NICEATM), moderator
retrieved from ICCVAM Communities of Practice Webinar 2024
Implementing Computational Approaches for Regulatory Safety Assessments
Monday, January 29, 2024 – 10:00 a.m.-12 noon EST
Register to view the webinar
Registration will be open until the webinar ends.
ICCVAM promotes the development and validation of toxicity testing methods that protect human health and the environment while replacing, reducing, or refining animal use. ICCVAM also provides guidance to test method developers and facilitates collaborations that promote the development of new test methods. This webinar, organized on behalf of ICCVAM by NICEATM, will discuss implementing computational approaches for regulatory safety assessments.
Computational toxicology methods can be useful for generating bioactivity predictions for chemicals for which limited toxicity data are available. They can also help users understand and interpret large, diverse bioactivity data sets, or predict how a chemical might behave in the body. However, users with limited experience with such methods may find it difficult to use them or interpret their outputs, or even understand how the methods could be applied in a specific context.
This webinar will discuss how to establish confidence in computational approaches for regulatory applications. Ongoing activities and key insights will be described in three presentations by speakers from the U.S. government and the private sector focusing on applications of tools such as structure-based models to predict chemical bioactivity and pharmacokinetic models to support understanding of chemical metabolism and disposition.
Agenda
Introductions: Helena Hogberg and Nicole Kleinstreuer, NIEHS/NICEATM
Presentations:
Michael Lowit, U.S. Environmental Protection Agency Office of Pesticide Programs
Pras Pathmanathan, U.S. Food and Drug Administration Center for Devices and Radiological Health
Jon Arnot, Arnot Research and Consulting
Q&A: Emily Reinke, Inotiv (contractor supporting NICEATM), moderator
retrieved from ICCVAM Communities of Practice Webinar 2024
